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"If we could re-grow and replace worn-out tissue [in other body parts], that would have tremendous implications," Sharlip said. View this table: In this window In a new window Treating heart disease risk factors Cialis Lipid profile: This blood test measures the level of lipids (fats), like cholesterol. High levels may indicate atherosclerosis (hardening of the arteries), which can affect blood circulation in the penis. Diabetes mellitus also causes erectile dysfunction by damaging both sensory and autonomic nerves, a condition called diabetic neuropathy. Smoking cigarettes, obesity, poor control of blood glucose levels, and having diabetes mellitus for a long time further increases the risk of erectile dysfunction in diabetes. In addition to atherosclerosis and/or neuropathy causing ED in diabetes, many diabetic men develop a myopathy (muscle disease) as their cause of ED in which the compliance of the muscle in the corpora cavernosa is decreased and clinically this presents as an inability to maintain the erection. For additional information, please read the Diabetes article.